Institutes of Science
Peter Kharchenko, PhD
Dr. Peter Kharchenko is a Principal Investigator at the Altos Labs San Diego Institute of Science.
Prior to joining Altos, Peter was a Gilbert S. Ommen Associate Professor of Biomedical Informatics at Harvard Medical School. His group has developed key methods for genomic analysis of single cells, enabling statistical separation of distinct cellular states, detection of genomic aberrations in transcriptional data, and inference of cellular dynamics from snapshots of cellular state. His group has also applied these approaches to study the organization of different tissues and the impact of diseases ranging from cancer to schizophrenia. At Altos, Peter’s group studies how cells coordinate their activity within complex biological tissues, how these mechanisms break down in the context of aging or disease, and investigate the potential interventions that may improve tissue function. Much of the effort is focused on development and application of novel statistical methods and computational tools for understanding tissue function, including analysis of multi-omics and spatial assays.